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Contraindicated (one)pentobarbital will decrease the extent or influence of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.buprenorphine transdermal and pentobarbital the two enhance sedation. Prevent or Use Alternate Drug. Limit use to patients for whom option cure options are inadequatepentobarbital will lessen the

pentobarbital will minimize the level or outcome of netupitant/palonosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Netupitant is principally metabolized by CYP3A4; stay clear of use in individuals who will be chronically employing a solid CYP3A4 inducerpentobarbital increases toxicity of buprenorphine